Dental Implants Research Today is a free monthly online journal that collates and summarizes the latest research about Dental Implants, including details on dentistry, surgery, tooth implants. | ||||||||
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Effect of thin carbonate-containing apatite (CA) coating of titanium fiber mesh on trabecular bone response.Hayakawa T, Takahashi K, Okada H, Yoshinari M, Hara H, Mochizuki C, Yamamoto H, Sato M Department of Dental Biomaterials, Nihon University School of Dentistry, 2-870-1, Sakaecho-nishi, Matsudo, Chiba 271-8587, Japan. hayakawa.tohru@nihon-u.ac.jp The influence of thin carbonate-containing apatite (CA) coating on trabecular bone response to cylindrical titanium fiber mesh (porosity of 85%, pore size of 200-300 microm, 2.8 mm diameter x 6 mm length) implants was investigated. Thin CA coatings were deposited by the so-called molecular precursor method. Molecular precursor solution was obtained by adding dibutylammonium diphosphate salt to Ca-EDTA/amine ethanol solution by adjusting Ca/P = 1.67. Sintered cylindrical titanium fiber mesh was immersed into molecular precursor solution and then tempered at 600 degrees C for 2 h. The immersion and tempering process was repeated three times. An adherent thin CA film could be deposited on the inside of titanium fiber mesh. After the immersion of a CA-coated titanium fiber mesh in simulated body fluid, apatite crystals precipitated on the titanium fiber mesh. Uncoated and CA-coated titanium fiber mesh was inserted into the trabecular bone of the left and right femoral condyles of rabbits. Histological and histomorphometrical evaluation revealed a significantly greater amount of bone formation inside the porous area of the CA-coated titanium fiber mesh after 12 weeks of implantation. The present results suggested that a thin CA-coated titanium mesh has better osteoconductivity and will be useful for a three-dimensional scaffold. Published 19 March 2008 in J Mater Sci Mater Med, 19(5): 2087-96.
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