Dental Implants Research Today is a free monthly online journal that collates and summarizes the latest research about Dental Implants, including details on dentistry, surgery, tooth implants.
Human dental pulp progenitor cell behavior on aqueous and hexafluoroisopropanol based silk scaffolds.
Zhang W, Ahluwalia IP, Literman R, Kaplan DL, Yelick PC
Division of Craniofacial and Molecular Genetics, Department of Oral and Maxillofacial Pathology, Tufts University School of Dental Medicine, Boston, Massachusetts.
Silk scaffolds have been successfully used for a variety of tissue engineering applications due to their biocompatibility, diverse physical characteristics, and ability to support cell attachment and proliferation. Our prior characterization of 4-day postnatal rat tooth bud cells grown on hexafluoro-2-propanol (HFIP) silk scaffolds showed that the silk scaffolds not only supported osteodentin formation, but also guided the size and shape of the formed osteodentin. In this study, interactions between human dental pulp cells and HFIP and aqueous based silk scaffolds were studied under both in vitro and in vivo conditions. Silk scaffold porosity and incorporation of RGD and DMP peptides were examined. We found that the degradation of aqueous based silk is much faster than HFIP based silk scaffolds. Also, HFIP based silk scaffolds supported the soft dental pulp formation better than the aqueous based silk scaffolds. No distinct hard tissue regeneration was found in any of the implants, with or without additional cells. We conclude that alternative silk scaffold materials, and hDSC pre-seeding cell treatments or sorting and enrichment methods, need to be considered for successful dental hard tissue regeneration. Research and technology has advanced so much in the past few years and dentists should be familiar with henryschein.com dental supplies and other companies that provide the resources for their practice.
Published 5 May 2011 in J Biomed Mater Res A, 97(4): 414-22.
Articles on Dental Implants published 5 May 2011:
Manufacturing of individual biodegradable bone substitute implants using selective laser melting technique. J Biomed Mater Res A, 97(4): 466-71.
The additive manufacturing technique selective laser melting (SLM) has been successfully proved to be suitable for applications in implant manufacturing. SLM is well known for metal parts and offers direct manufacturing of three-dimensional (3D) parts with high bulk density on the base of individual 3D data, including computer tomography models of anatomical structures. Furthermore, an interconnecting porous structure with defined and reproducible pore size can be integrated during the design ... [Abstract] [Full-text]
Histomorphometric analysis following augmentation of the posterior mandible using cancellous bone-block allograft. J Biomed Mater Res A, 97(4): 509-13.
The present study was conducted to histologically and histomorphometrically evaluate the application of cancellous bone-block allografts for the augmentation of the posterior atrophic mandible. Twenty-four consecutive patients underwent augmentation with cancellous bone-block allografts in the posterior mandible. A bony deficiency of at least 3 mm horizontally and/or vertically according to CT para-axial reconstruction served as inclusion criteria. Following 6 months, 85 implants were placed ... [Abstract] [Full-text]
Background: Various sinus-lift techniques have been described in the literature. The aim of this study was to evaluate the efficacy of the Cosci transalveolar sinus-lift technique in terms of implant survival, marginal bone loss and complications. Methods: A total of 538 patients were examined and following exclusion and inclusion criteria a sample of patients was included with a mean follow-up of 5 years. Implants with smooth or tapered surface were considered. Therefore only sinus lifts with ... [Abstract] [Full-text]
Articles on Dental Implants published 4 May 2011:
Purpose: The retentive forces and the strain energies absorbed during dislodging of implant overdenture stud attachments are useful parameters to consider in the selection of attachments. The purpose of this study was to compare the retentive forces and strain energies of the Nobel Biocare standard ball, Nobel Biocare newer generation ball (Yorba Linda, CA), Zest Anchor, Zest Anchor Advanced Generation (Escondido, CA), Sterngold-Implamed ERA white, and Sterngold-Implamed orange attachments ... [Abstract] [Full-text]
Articles on Dental Implants published 3 May 2011:
Effects of soft palate implants on acoustic characteristics of voice and articulation. J Voice, 25(3): 381-6.
Immediate implant loading is a viable treatment method for selected cases. One of the greatest advantages of this method is the virtual surgery, which precedes the actual clinical treatment and eliminates any need for last minute decisions. The actual surgery time is decreased, since all steps are predetermined. Additionally, no flaps have to be elevated, resulting in preservation of periimplant soft tissues, vascularization of the underlying bone, fewer postoperative complications, and minimal ... [Abstract] [Full-text]
Osseointegration is the most preferable interface of dental implants and newly formed bone. However, the cavity preparation for dental implants often gives rise to empty lacunae or pyknotic osteocytes in bone surrounding the dental implant. This study aimed to examine the chronological alternation of osteocytes in the bone surrounding the titanium implants using a rat model. The distribution of the osteocytic lacunar canalicular system (OLCS) in bone around the titanium implants was examined by ... [Abstract] [Full-text]
Articles on Dental Implants published 2 May 2011:
Isotropic micropatterned silica coatings on zirconia induce guided cell growth for dental implants. Dent Mater, 27(6): 581-9.
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